Bunavail Explained: How Buprenorphine and Naloxone Help Overcome Opioid Addiction

Q: What is Bunavail used for?

Bunavail is used to treat opioid dependence (opioid use disorder) . It helps reduce cravings and withdrawal symptoms while blocking the euphoric effects of opioids. It’s typically prescribed as part of a Medication-Assisted Treatment (MAT) plan along with counseling and behavioral therapy.

Q: How is Bunavail different from Suboxone?

Both Bunavail and Suboxone contain buprenorphine and naloxone , but Bunavail comes in a buccal film that sticks inside your cheek for better absorption and a milder taste. Suboxone is usually taken under the tongue (sublingual film or tablet).

Q: Is Bunavail addictive?

Bunavail contains buprenorphine , which can cause dependence if misused. However, when taken as prescribed under medical supervision, it helps manage addiction safely and prevents misuse by including naloxone , which blocks the opioid “high.”

Table of Contents

What Is Bunavail?

Bunavail is a prescription medication used to treat opioid dependence or opioid use disorder.
It contains two active ingredients: buprenorphine and naloxone, which work together to reduce cravings and prevent misuse. Bunavail is designed as a buccal film that sticks to the inside of your cheek and dissolves quickly.

How Bunavail Works

Bunavail combines two key components:

Buprenorphine — a partial opioid agonist that helps relieve withdrawal symptoms and cravings without producing a strong “high.”
Naloxone — an opioid antagonist that blocks the euphoric effects of opioids if the drug is misused (e.g., injected).

By targeting opioid receptors safely, Bunavail helps patients stabilize their condition and focus on recovery.

Why Doctors Prescribe Bunavail

Bunavail is prescribed as part of a Medication-Assisted Treatment (MAT) plan. It works best when combined with counseling, therapy, and support programs.

Key reasons doctors choose Bunavail:

Reduces withdrawal discomfort
Lowers the risk of opioid relapse
Has less potential for abuse
Offers convenient and discreet buccal film dosing

Available Dosages and Administration

Bunavail is available in three strengths:

2.1 mg / 0.3 mg
4.2 mg / 0.7 mg
6.3 mg / 1 mg

The first number refers to buprenorphine content, and the second refers to naloxone.
The film is placed inside the cheek (buccal mucosa) and allowed to dissolve completely—do not chew or swallow it.

Possible Side Effects

Like any medication, Bunavail can cause side effects.
Common side effects:

Headache
Nausea or vomiting
Constipation
Sweating
Mouth or gum irritation
Drowsiness

Serious side effects (seek medical help):

Breathing difficulties
Confusion or extreme drowsiness
Signs of allergic reaction (rash, swelling, or difficulty breathing)

Bunavail vs Suboxone

Feature	Bunavail	Suboxone
Form	Buccal film (cheek)	Sublingual film/tablet (under tongue)
Bioavailability	Higher absorption	Moderate absorption
Taste	Milder	Stronger
Dosage forms	2.1/0.3, 4.2/0.7, 6.3/1 mg	2/0.5, 8/2 mg
Manufacturer	BioDelivery Sciences	Indivior

Verdict:
Bunavail provides similar effectiveness with better absorption and a more comfortable taste, making it a preferred choice for some patients.

Precautions and Warnings

Avoid alcohol and sedatives — they can cause dangerous breathing problems.
Do not drive or operate machinery until you know how the drug affects you.
Pregnant or breastfeeding women should consult a doctor before use.
Store Bunavail securely to prevent misuse.

Tips for Best Results

Follow your doctor’s dosing instructions carefully.
Combine medication with therapy and lifestyle support.
Do not stop taking Bunavail suddenly — it may cause withdrawal symptoms.
Avoid sharing your medication with others.

External References

Conclusion

Bunavail (Buprenorphine/Naloxone) is a trusted and effective treatment for opioid dependence. With its advanced buccal delivery system, it offers higher absorption, fewer side effects, and lower risk of misuse compared to traditional options like Suboxone.
When used responsibly and combined with professional therapy, Bunavail helps patients regain control over their lives and achieve long-term recovery.

What is Bunavail used for?

Bunavail is used to treat opioid dependence (opioid use disorder). It helps reduce cravings and withdrawal symptoms while blocking the euphoric effects of opioids. It’s typically prescribed as part of a Medication-Assisted Treatment (MAT) plan along with counseling and behavioral therapy.

How is Bunavail different from Suboxone?

Both Bunavail and Suboxone contain buprenorphine and naloxone, but Bunavail comes in a buccal film that sticks inside your cheek for better absorption and a milder taste. Suboxone is usually taken under the tongue (sublingual film or tablet).

Is Bunavail addictive?

Bunavail contains buprenorphine, which can cause dependence if misused. However, when taken as prescribed under medical supervision, it helps manage addiction safely and prevents misuse by including naloxone, which blocks the opioid “high.”